The Sustain Build

is great for laning and harassing due to the healing from the talents. Ossein Renewal provides alot of missing health. Here I see the Entomb being a mandatory ability since it can close paths. The Entomb can catch a safe kill, it can save players by catching an enemy, in fights it can also take out the most important enemy from the fight!
Drain Hope has a decent range without talents and will regain plenty of health, with Drain Momentum (lvl 13 talent) it can be a bully (and a saver with Wraith Walk on CD) without having your movement speed reduced.
Consume Vitality (lvl 16 talent) is an awesome heal! Every 8 seconds you may use it to heal up to 10% health in addition to it's slow and big damage.
Gather as many health globes as you can for the permanent health regen, and the ability to gather the regen globes while Undying.

The Drain Build

has been tested once so without futher inspection, it did give me a big boost in damage.

The Offensive Build

will let you Wraith Walk more safer due to the reduced damage taken. You also have more slow with a slightly boost in damage & basic attack healing.