This build is designed to play to Valeera's strengths as a burst mage, who can lock-down a single target, and apply vulnerability. With a bit of communication from your team, you can find this build very rewarding.

Level 1/4/7: Talents are meant to synergize with each other. As long as you land Sinister strike it's left on a 1 second cooldown. So it makes sense that you want to be able to spam it. Vigor allows you the energy to spam Sinister Strike more freely, as does Relentless Strikes. Mutilate at 7 ensures that you are doing good damage with Sinister Strike spam.

Level 10: Smoke Bomb is fairly obvious choice of ultimate, and it should be taken every game.

Level 13: When opening up as a stealth character, you have to be careful since your outline can be seen, Elusiveness at 13 grants you extra move speed, making you harder to pin down, and it allows you an easier time to make it to the ideal target in a team-fight.

Level 16: Expose Armor at 16 highlights Valeera's strength as a burst mage, who works well with her team to blow-up a single target.

Level 20: Not only is having a lower cooldown on vanish ideal for your survival, but it also means you'll cheap-shot and garrote available more often, which is quite nice.

Combo Options:
3 CP -> Eviscerate (Make them vulnerable and call it out)
2 CP -> Cheap Shot -> Eviscerate (Stunned Target that is now Vulnerable)
2 CP -> Garrote -> Eviscerate (Use this on a character with a blink like Li-Ming)

Ever have one of those games where you just can't help but call everyone on your team new? Ever realized that you are the only competent player on your team, and if you want something done, ya gotta do it yourself? Well then this build is for you! This build is designed for straight burst damage out of Valeera, with minimal reliance on your team to follow up and get stuff done.

Level 1/4/7/10: Very Much the same as the standard build for all the same reasons (read above.)

Level 13: Death from Above allows Valeera to follow up on the next target for a quick kill after making a strong opener on your primary target. I like to follow this up with a smoke bomb to try and bait the enemy team into overstaying their welcome.

Level 16: Seal Fate gives more damage to our already spammable sinister strike, and allows it to do a very reliable consistent chunk of damage by our self without reliance on our team. If a member of our team does happen to land a stun, root, or silence, we can follow that up quite easily.

Level 20: Night Stalker

Combos:
Cheap Shot -> Sinister Strike -> Eviscerate (This one puts you at full CP, and bursts fast)
Garrote -> Sinister Strike -> Eviscerate -> Sinister Strike

This build on paper seems to have a lot of synergy, but it is still under testing. The biggest thing I'm considering is taking seal fate at 16, since reliably auto attacking can oftentimes be hard.