Newly updated Artanis now offers more combinations to play around with.

Blade Reaper seeks to keep your Blade Dash up as much as possible, clears waves, and takes camps.
Shield Parry seeks to keep your Shield Overload up as much as possible and blinds enemies.
Prism Purifier seeks to set up Purifier Beam hero kills, plant/dragon/mech kills.
Zealous Titan seeks to dive onto a single hero with % damage, and other damage bonuses.
Real-Time Strategy seeks to deal non-hero damage at the highest level without requiring a hero to surge with.

Crowd Control will always be your biggest threat.